Sun exposure and associated risks: Insight from an international survey with a focus on the organ transplant recipient population.

person Delphine Kerob La Roche-Posay International, Levallois-Perret, France info_outline Delphine Kerob, Brigitte Dreno, Thierry Passeron, Susana Puig, Cl Goh, Henry Lim, Fatimata Ly, H. Kang, A. Morita, Jorge Ocampo, Sergio Schalka, L. Wei, Caroline Lefloch, Anne-Laure Demessant, Jean Krutmann

Authors person Delphine Kerob La Roche-Posay International, Levallois-Perret, France info_outline Delphine Kerob, Brigitte Dreno, Thierry Passeron, Susana Puig, Cl Goh, Henry Lim, Fatimata Ly, H. Kang, A. Morita, Jorge Ocampo, Sergio Schalka, L. Wei, Caroline Lefloch, Anne-Laure Demessant, Jean Krutmann Organizations La Roche-Posay International, Levallois-Perret, France, Nantes Université, Nantes, France, Côte d’Azur University, Nice University Hospital Center, INSERM U1065, C3M, Nice, France, Hospital Clinic of Barcelona, Barcelona, Spain, National Skin Centre, Singapore, Singapore, Singapore, Henry Ford Health System, Detroit, MI, Cheikh Anta Diop Dakar University, EPS Institute of Social Hygiene, Dakar, Senegal, Ajou University School of Medicine, Suwon, South Korea, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, Medical Faculty University Hospital of Nuevo Leon, Monterrey, Mexico, Chemistry Institute of Sao Paulo University, Sao Paulo, Brazil, The General Hospital of Air Force PLA, Beijing, China, IUF Leibniz Research Institute for Environmental Medicine, Dusseldorf, Germany Abstract Disclosures Research Funding Pharmaceutical/Biotech Company La Roche Posay Background: This survey investigates knowledge and behaviors regarding sun exposure among population who have been treated with immunosuppressive anti-graft rejection drugs because of an organ transplantation. Methods: The survey (N = 17,001) was conducted online in 17 countries (5 continents) from 28 September-18 October 2021. Automated selection from the Ipsos online Panel ensured samples of 1,000 individuals in each country fit the quotas method based on gender, age, employment status, and country regions. Data covered demographics, phototype, exposure habits and practices, knowledge and understanding of risks. The current focus in this abstract was defined as individuals who have been treated with immunosuppressive anti-graft rejection drugs because of an organ transplantation. Results: This sub population represents 3% of the general population (n = 434), it comprised 65% men, average age was 39.7 years (SD:14.6) and 57% were of phototype 1-2. 85% were aware of sun-related skin-health issues, a similar awareness among general population (88%). 79% did know that sun protection is useful when the weather is overcast, a better knowledge compared to the general population (61%). Furthermore, 75% did understand the difference between UVA and UVB vs 30% in the general population. But, 69% indicated it was safe to expose themselves without protection when already tanned, a much larger misconception compared to the general population (23%). Only 46% systematically/often use all protections measures during exposure; still a higher practice compared to the general population (12%). And, 63% said they protected from the sun all year round, a better habit compared to the general population (23%). However, during sun exposure, among the 93% who declared using sunscreen, 85% applied sunscreen only once or twice a day, a worse practice compared to the general population (74%). And when already tanned 37% decreased frequency of application and/or used lower protection (44% among general population). 89% regretted not having previously used better protection, a much stronger regret compared to the general population (57%). Conclusions: Although individuals who have been treated with immunosuppressive anti-graft rejection drugs because of an organ transplantation had better knowledge and behavioral attitudes compared to the general population, this survey shows that even a population at high risk of skin cancers and having a regular medical follow-up does not sufficiently perceive the importance of photoprotection in a prevention objective. This leads to discuss the implementation of new information tools with more impact.