Clinical trial

Is There a Genetic Predisposition for Acute Stress-induced (Takotsubo) Cardiomyopathy: The GENETIC Study

Name

2-025-18

Description

Acute stress-induced (takotsubo) cardiomyopathy or broken heart syndrome presents like a heart attack, classically is triggered by intense emotional or physical stress and can have serious health consequences. In the current study the investigators wish to establish whether there is a genetic predisposition making certain people more susceptible to this condition. This could also have implications for their families.

Trial arms

Trial start

2019-03-12

Estimated PCD

2028-12-31

Trial end

2028-12-31

Status

Recruiting

Treatment

Blood collection for genetic analysis

Arms:

Takotsubo Case Arm

Size

700

Primary endpoint

Genome Wide Association Study

At baseline

Eligibility criteria

Inclusion Criteria: * All patients who have been diagnosed with Takotsubo cardiomyopathy in Scotland between 2010 to date. * Familial cases elsewhere in the world who would be willing to participate. Exclusion Criteria: * Unwillingness to participate

Protocol

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'NA', 'interventionModel': 'SINGLE_GROUP', 'interventionModelDescription': 'Single group observational study.', 'primaryPurpose': 'OTHER', 'maskingInfo': {'masking': 'NONE'}}, 'enrollmentInfo': {'count': 700, 'type': 'ESTIMATED'}}

Updated at

2023-12-08

1 organization

1 product

1 indication

Organization

University of Aberdeen

Product

Blood collection

Indication

Takotsubo cardiomyopathy