Clinical trial

Efficacy and Safety of Airway Clearance Technique by Oscillation and Lung Expansion in Patients With Bronchiectasis

Name

20230901

Description

The goal of this prospective randomized controlled trial is to explore the efficacy and safety of Oscillation and Lung Expansion-a airway clearance technology-in bronchiectasis. Participants will receive Oscillation and Lung Expansion or postural drainage randomly in this study. and the symptom, quality of life scores and amount of expectoration will be compared between the two groups.

Trial arms

Trial start

2023-09-01

Estimated PCD

2025-09-01

Trial end

2026-05-01

Status

Recruiting

Treatment

Oscillation and Lung Expansion

A novel airway clearance technology

Arms:

Oscillation and Lung Expansion

Postural drainage

A type of physical therapy used to treat respiratory diseases by changing the patient's body position so that sputum is drained down the respiratory tract so that it can be more easily expelled from the body.

Arms:

postural drainage

Anti-infective therapy

Antibiotics were used in these patients.

Arms:

Oscillation and Lung Expansion, postural drainage

Mucolytic

Mucolytics were used in these patients.

Arms:

Oscillation and Lung Expansion, postural drainage

Size

Primary endpoint

sputum volume in 24h

2 weeks

Eligibility criteria

Inclusion Criteria: * patients with acute exacerbation of bronchiectasis Exclusion Criteria: * Haemoptysis greater than 50ml * state of endangerment * pneumothorax * Lung surgery history within 6 months * Severe heart, brain and nervous system diseases

Protocol

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'Patients will be randomized into one of the two groups. No cross-over of the study group will be made', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'NONE'}}, 'enrollmentInfo': {'count': 96, 'type': 'ESTIMATED'}}

Updated at

2024-05-01

1 organization

Organization

Shanghai Pulmonary Hospital, Shanghai, China