The Effect of the Anticholinergic Burden on Complications and Mortality Following Elective Coronary Artery Surgery in Patients Over 60 Years

AnkaraCHBilkent.1

Many drugs have anticholinergic activity. This means that it blocks the muscarinic binding of the neurotransmitter acetylcholine. In this study, the anticholinergic burden of the patients in the perioperative period will be calculated with the Anticholinergic Cognitive Burden Scale (ACBS) and patients with a score of 1 or above will be included in the study. Anticholinergic load of drugs used in the intraoperative period; Its effect on postoperative hospital stay, morbidity and mortality following elective heart surgery will be investigated.

2024-01-01

2024-12-01

2024-12-30

Recruiting

Early phase I

120

Inclusion Criteria: * Patients undergoing elective coronary artery bypass surgery * Patients with high anticholinergic burden Exclusion Criteria: * All other procedures except isolated coronary bypass surgery * Patients with low anticholinergic burden * Patients whose records cannot be accessed through the data system

{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE4'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'QUADRUPLE', 'whoMasked': ['PARTICIPANT', 'CARE_PROVIDER', 'INVESTIGATOR', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 120, 'type': 'ESTIMATED'}}

2024-04-05