Efficacy Methadone for Management Postoperative Pain After the Use of Anesthesia Intravenous in Laparoscopic Cholecystectomy

P03/13

The aim of this study is to compare the efficacy of methadone versus morphine in dealing with postoperative pain, in laparoscopic cholecystectomy under total intravenous anesthesia (TIVA); Efficacy is defined in terms of the difference of milligrams in morphine used as rescue analgesia postoperatively. Our hypothesis is that methadone is more effective than morphine for postoperative pain treatment.

2013-03-01

2013-08-01

2013-09-01

Completed

86

Inclusion Criteria: * Patients undergoing laparoscopic cholecystectomy in the Almirante Nef Naval Hospital * Patients ASA 1 or 2 Exclusion Criteria: * Patients with renal insufficiency (creatinine\> 2.0 mg / dl) * Patients with a history of liver failure * Patients with BMI\> 35 kg/m2 * Patients with hypersensitivity to the drugs in question * History of chronic use of opioids * Need for conversion to open surgery

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'CARE_PROVIDER']}}, 'enrollmentInfo': {'count': 86, 'type': 'ACTUAL'}}

2023-09-26