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Clinical trial

Genetic and Biological Background and Follow-up of Different Phenotypes of Coeliac Disease

ID
Name
R22088
Description
The main purpose of this study is to investigate genetic, serological, immunological and microbiata diversities between different coeliac disease phenotypes and to discover applicable prognostic markers for specific phenotypes.
Trial arms
Trial start
2022-11-08
Estimated PCD
2027-12-31
Trial end
2030-12-31
Status
Recruiting
Treatment
Genetic predisposition
Assessment of genetic predisposition to various celiac disease phenotypes. No intervention.
Arms:
Coeliac disease patients, Healthy controls
Size
3500
Primary endpoint
Non-HLA variant association
baseline
Eligibility criteria
Inclusion Criteria: * Cohorts 1 and 2: coeliac disease or dermatitis herpetiformis diagnosis * Cohort 3: friend or non-related family member of coeliac disease or dermatitis herpetiformis patient Exclusion Criteria: * Cohorts 1-3: Age \<18 years * Cohorts 1 and 2: coeliac disease or dermatitis herpetiformis diagnosis not confirmed * Cohort 3: coeliac disease or dermatitis herpetiformis diagnosis
Protocol
{'studyType': 'OBSERVATIONAL', 'patientRegistry': False, 'designInfo': {'observationalModel': 'CASE_CONTROL', 'timePerspective': 'CROSS_SECTIONAL'}, 'enrollmentInfo': {'count': 3500, 'type': 'ESTIMATED'}}
Updated at
2024-04-16

1 organization

1 product

2 indications

Organization
Tampere University Hospital
Product
Genetic predisposition
Indication
Celiac Disease
Indication
Dermatitis Herpetiformis