The Effect of Preprocedural Subanesthetic Ketamine for Pain and Anxiety in Patients During Thoracic Epidural Catheterization: A Randomized Trial

KEAH-238

The thoracic epidural catheterization (TEC) can be both uncomfortable and fearful for patients when done awake with the thought that the procedure may be painful. The aim of this study was to assess the effect of subanesthetic intravenous ketamine administration on pain and anxiety during the TEC procedure.

2013-06-01

2023-01-01

2023-06-01

Completed

Early phase I

60

Inclusion Criteria: * Patients who underwent elective thoracic surgery via thoracotomy * Patients with ASA physical status I-III Exclusion Criteria: * Describing chronic pain, * Have a bleeding disorder, * Having a history of analgesia drug use, * Have a history of liver disease, * Have serious metabolic and endocrine problems, * Have a history of allergy to ketamine and local anesthetics, * Have an infection in the intervention area, * Rejecting thoracic epidural catheter, * Describing acute pain in any part of the body during the preoperative evaluation, * Thoracic epidural catheter duration greater than five minutes (time from needle entry to catheter placement) * Patients requiring more than two Tuohy injection attempts

{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE3'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'This study was designed as a randomized, prospective study', 'primaryPurpose': 'PREVENTION', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['PARTICIPANT']}}, 'enrollmentInfo': {'count': 60, 'type': 'ACTUAL'}}

2024-03-15