Effect of Mannitol on Recovery Pattern After Orthognathic Surgery, a Prospective Randomized Double Blind Controlled Study.

RC1-3-2024

The aim of this study is to test, whether mannitol infusion in different doses will affect recovery pattern? the investigators hypothesized that infusion of mannitol in doses of 0.5 gm/kg before recovery from anesthesia after orthognathic surgery shortens patients' recovery time, and improves recovery quality, as well as postoperative cognitive function better.

2024-03-01

2024-06-01

2024-08-01

Active (not recruiting)

60

Inclusion Criteria: * Age: 18-65 years * ASA status I and II patient. * No contraindication to use of mannitol. Exclusion Criteria: * ASA III and IV status * Extreme of age: paediatric and geriatric patients * Severe cardio respiratory, rheumatological or endocrinal disorders * Pregnancy and lactation * Contraindications to the use of mannitol, e.g. serum osmolality \> 330, renal failure systemic hypertension, proved intra-cranial brain haemorrhage or sub-dural haematoma and hypotension.

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2024-05-06