Clinical trial
Exploring the Genetics of Neuropathic Pain
Name
2017/1593
Description
In the present study the investigators will search for new genetic variants relevant for the development of neuropathic pain.
Trial arms
Trial start
2018-08-01
Estimated PCD
2027-01-01
Trial end
2027-12-31
Status
Recruiting
Treatment
Nerve conduction Studies
Patients will be genotyped for comparison of patients With and without pain, With different clinical subgroups as mentioned.
Arms:
Carpal tunnel syndrome with pain, Carpal tunnel syndrome without pain, Diabetic polyneuropathy with pain, Diabetic polyneuropathy without pain, Polyneuropathy with pain, Polyneuropathy without pain
Other names:
Genetical analysis
Size
5000
Primary endpoint
Genetic variants associated with neuropathic pain.
Baseline
Phenotype; neuropathic pain yes/no
Baseline
Phenotype; subgroup analysis of patients with neuropathic pain based on grading of pain
Baseline
Eligibility criteria
Inclusion Criteria:
1. The patient is between 18 and 70 years old.
2. The patient has consented.
3. The patient is referred for evaluation of possible distal symmetric polyneuropathy (DSPN).
4. The patient has filled out the questionnaires.
Exclusion Criteria:
1. The patient is too sick to participate (eg. bedridden, fever).
2. The patient is unable to consent (eg. dementia, speech problems, psychiatric disorder).
3. Inflammatory acute polyneuropathy.
Protocol
{'studyType': 'OBSERVATIONAL', 'patientRegistry': True, 'targetDuration': '1 Day', 'designInfo': {'observationalModel': 'CASE_CONTROL', 'timePerspective': 'CROSS_SECTIONAL'}, 'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': 'Whole blood + blood for Expression analysis'}, 'enrollmentInfo': {'count': 5000, 'type': 'ESTIMATED'}}
Updated at
2023-11-07
1 organization
1 product
3 indications
Organization
Oslo University HospitalProduct
Nerve conduction StudiesIndication
Neuropathic PainIndication
Genetic PredispositionIndication
Polyneuropathies