Clinical trial
Assessment of Collagen Loaded With Bone Marrow Aspirate Concentrate Versus Autograft on Marginal Bone Changes Around Immediate Implants in Esthetic Zone. A Randomized Controlled Clinical Trial
Name
BMAC around immediate implants
Description
The present study aims to evaluate the effect of utilization of BMAC/ collagen on marginal bone changes around immediate implants in the esthetic zone of maxilla.
Methodology: Twenty dental implants will be installed in the esthetic zone and patients will be randomly divided into two groups:
study group: The jumping gap surrounding the immediate implants will be grafted with BMAC/collagen, whereas in the control group, autograft from the chin will be used to fill the defect. Cone beam CT (CBCT) will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around implants.
.
Trial arms
Trial start
2023-01-25
Estimated PCD
2024-10-01
Trial end
2024-12-01
Status
Recruiting
Treatment
BMAC/ collagen
Bone marrow aspirate concentrate loaded on collagen in the peri-implant defect
Arms:
BMAC/ collagen
Other names:
Bone marrow aspirate concentrate group
Autograft harvesting from chin
Autograft
Arms:
Autograft
Other names:
Autograft group
Size
20
Primary endpoint
Marginal bone changes
4 months
Eligibility criteria
Inclusion Criteria:
* Patients with non- restorable teeth in esthetic zone
* Patients above 18 us
* Highly motivated patients.
Exclusion Criteria:
* patients with systemic diseases • immunocompromised patients . Patients with bleeding disorders
Protocol
{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 20, 'type': 'ESTIMATED'}}
Updated at
2024-03-28
1 organization
1 product
2 indications
Organization
Cairo UniversityProduct
BMAC CollagenIndication
Implant Site ReactionIndication
Dental Implant