Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy - a Randomized, Double-blind, Placebo-controlled Trial

Eudract: 2018-001261-16

Betamethasone is currently given routinely in conjunction with tonsillectomy surgery at the majority of Ear, Nose \& Throat clinics in Sweden. The scientific evidence regarding the effects of betamethasone in adults is limited when it comes to postoperative nausea (PONV), pain and postoperative bleeding.

2019-09-10

2025-06-20

2025-12-15

Recruiting

Early phase I

100

Inclusion Criteria: Signed informed consent Age over 12 years Planned for elective bilateral tonsillectomy Exclusion Criteria: * • Insulin dependent diabetes mellitus * NSAID or corticosteroid intolerance * Pregnancy * Gastric ulcer * Immunodeficiency * Treatment for chronic pain * Psychiatric disorders

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2024-05-14