Evaluating the Impact of Ketamine Gargling on Post Intubation Sore Throat: A Randomized Controlled Trial.

Ketamine for POST

Tracheal intubation often causes trauma to the airway mucosa, leading to postoperative sore throat (POST), which has been reported to occur in 21-65% of cases. While considered a minor complication, POST can contribute to postoperative discomfort and patient dissatisfaction.

2024-04-25

2024-08-15

2024-09-20

Not yet recruiting

80

Inclusion Criteria: * Adult patients from both sex and aged between 18 and 45 years. * All participants were scheduled for elective laparoscopic appendectomy or cholecystectomy under general anesthesia. * Classified as ASA (American Society of Anesthesiologists) I or II. * Intubation duration is less than 90 minutes. Exclusion Criteria: * Patients classified as ASA III or higher. * Patients exhibiting symptoms of sore throat prior to entering the operating room, or presenting with any respiratory illness or signs of respiratory infection. * Patients who smoke. * Patients with a history of allergy to drugs used in this study. * Patients who are addicted to steroid drugs (inhaled or oral). * Patients with predicted difficult airway and intubation, indicated by a Mallampati score of II or higher. * Obese patients with a BMI exceeding 35. * Patients with neurological diseases.

{'studyType': 'OBSERVATIONAL', 'patientRegistry': False, 'designInfo': {'observationalModel': 'COHORT', 'timePerspective': 'PROSPECTIVE'}, 'enrollmentInfo': {'count': 80, 'type': 'ESTIMATED'}}

2024-04-16