Comparative Evaluation of Melatonin Versus Mineral Trioxide Aggregate on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study

Melatonin- vital pulp therapy

The process of dental caries is dynamic and can be either reversible or irreversible depending on the balance between protective and pathologic factors in the oral cavity. Untreated dental caries causes pulpal injury, inflammation, and necrosis. Melatonin plays an essential role in the regulation of bone growth. The actions that melatonin exerts on odontoblasts may be similar to its action on osteoblasts.

2023-05-20

2024-05-20

2024-06-20

Recruiting

45

Inclusion Criteria: * 1- Apparently healthy and medically free children. 2- Their age ranges from 6-8 years. 3- Both boys and girls will be included. 4- Children should have mandibular permanent first molars with the following clinical and radiographic criteria. 4.1Restorable young permanent first molars. 4.2Absence of clinical evidence of pulp degeneration: * No history of spontaneous pain, history of night pain or pain that not relieved by analgesics. * No pain on percussion. * No mobility. * Absence of abscess, purulent sinus or soft tissue edema. * Bleeding should stop within 5 minutes after the amputated pulp stumps. Exclusion Criteria: * Internal root resorption. * External root resorption. * Inter radicular or periapical bone destruction (radiolucency) * A deep carious lesion radiologically that approaches the pulp

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2024-04-18