Clinical trial

CUHK Stroke Biobank

Name
crec no. 2014.582
Description
The purpose of the study are: 1. To make quality, characterized samples and related data available for future studies, including Genome Wide Association Studies (GWAS), genomics, and biomarker research; 2. To use these samples and related medical information to answer research questions aimed at understanding the genetics and underlying biology of acquired disease and injury to the brain, heart and blood vessels with the express purpose of advancing the search for effective modalities for prevention, treatment, and recovery; 3. To develop additional operational infrastructure to support this project across the Prince of Wales Hospital and divisions, including (1) tracking of patient consent, (2) management of collection and sample processing processes, (3) sample inventory and QC/QA processes, and (4) release of materials to investigators for further research.
Trial arms
Trial start
2015-06-15
Estimated PCD
2025-12-31
Trial end
2025-12-31
Status
Recruiting
Treatment
Gene expression or biomarkers exploration
Arms:
Atherosclerosis, Family members, Normal subjects
Size
500
Primary endpoint
Ischemic stroke-related genetics
Dec, 2025
Eligibility criteria
Inclusion Criteria: 1. Adult equal or more 18 years of age and Chinese ONLY. 2. Stroke patients, their family members, and/or the normal subjects without intracranial stenosis or extracranial stenosis, are eligible to join the study. 3. Subject is willing to have blood taken, cerebral spinal fluid and/or body tissue drawn for storage in the research bank. Exclusion Criteria: * None
Protocol
{'studyType': 'OBSERVATIONAL', 'patientRegistry': False, 'designInfo': {'observationalModel': 'OTHER', 'timePerspective': 'OTHER'}, 'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': '30ml of EDTA blood, buccal swab or saliva, body tissue, or cerebrospinal fluid to be collected'}, 'enrollmentInfo': {'count': 500, 'type': 'ESTIMATED'}}
Updated at
2023-08-30

1 organization

1 product

5 indications

Indication
stroke
Indication
Ischemic
Indication
Genetic Disease
Indication
Atherosclerosis
Indication
Cerebral