Clinical trial

Efficacy of Erector Spinae Plane Block on Postoperative Analgesia and Recovery After Off Pump Cardiac Surgery: A Randomised Trial

Name

2/2023 ANET10-2

Description

In this study the investigators will investigate the efficacy of ESPB as a part of Enhanced recovery after surgery on postoperative analgesia and recovery criteria after off pump cardiac surgery.

Trial arms

Trial start

2023-03-22

Estimated PCD

2023-10-10

Trial end

2023-12-25

Status

Completed

Treatment

Erector spinae block

After induction, the patients will be administered bilateral Erector spinae block with 20 ml of 0.25 % bupivacaine

Arms:

Erector spinae block group

Fentanyl

fentanyl boluses of 0.5-to-1 µg/kg titrated according to haemodynamic parameters.

Arms:

Erector spinae block group, control group

Size

Primary endpoint

Total intraoperative and postoperative opioid consumption

48 hours

Eligibility criteria

Inclusion Criteria: * age 18-70 years * ejection fraction of \> 45% * undergoing elective off-pump cardiopulmonary bypass surgery Exclusion Criteria: * vertebral anomalies * intra-aortic balloon pump in the preoperative period * acute myocardial infarction * local infection at the site of block * allergy to the local anesthetic used * morbid obesity, psychiatric disorders, neurologic deficits, alcohol and chronic opioid abuse, and patients with bleeding diathesis.

Protocol

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'OTHER', 'maskingInfo': {'masking': 'NONE'}}, 'enrollmentInfo': {'count': 50, 'type': 'ACTUAL'}}

Updated at

2024-03-19

1 organization

1 product

1 indication

Organization

Menoufia University

Product

Fentanyl

Indication

Postoperative Pain