Does Optimized General Anesthesia Care Reduce Postoperative Delirium In Older Patients Undergoing Hip Fracture Repair?

1212915

Postoperative delirium occurs in up to 65% of elders undergoing surgery for repair of a hip fracture and this complication is independently associated with increased morbidity, mortality, length of hospital stay, and placement in long-term care institutions. To date, the only intervention shown to be effective at minimizing postoperative delirium is a proactive geriatric consultation. This prospective randomized clinical trial will randomize 160 adults, aged 65 years or older, to either optimized general anesthesia or usual general anesthesia care for hip fracture surgery to determine if the optimized anesthesia management reduces the severity of postoperative delirium.

2015-06-01

2018-02-28

2018-02-28

Terminated

145

Inclusion Criteria: * Subject or legal representative has voluntarily signed the informed consent approved by the Institutional Review Board, * Hip fracture surgery scheduled under general anesthesia * Subject is 65 years or older on the day of surgery Exclusion Criteria: * Inability to follow directions or comprehend the English language * Severe uncorrected visual or auditory handicaps * Delirium at screening or baseline * Emergency surgery

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'SINGLE', 'maskingDescription': 'The individuals assessing the patients for delirium after surgery will be unaware of the treatment in the operating room.', 'whoMasked': ['OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 145, 'type': 'ACTUAL'}}

2023-10-17