Clinical trial

TAP Block With Dexamethasone Versus TAP Block With Methyl-prednisolone as a Pain Treatment Modality After Total Abdominal Hysterectomy Procedures: Randomized Controlled Trial

Name
N-139-2023
Description
The aim of this work to compare between the efficacy of ultrasound guided TAP block with dexamethasone as an adjuvant versus ultrasound guided TAPB with methyl prednisolone as an adjuvant to local anesthetic for postoperative pain management in lower abdominal hysterectomy procedures.
Trial arms
Trial start
2023-12-01
Estimated PCD
2024-04-20
Trial end
2024-04-20
Status
Completed
Treatment
TAPB with dexamethasone as an adjuvant to local anesthetics
patients will receive TAPB with dexamethasone as an adjuvant to bupivacaine and lidocaine local anesthetics
Arms:
Group TAPB-D (n=25)
TAPB with methylprednisolone as an adjuvant to local anesthetics
patients will receive TAPB with methylprednisolone as an adjuvant to bupivacaine and lidocaine local anesthetics
Arms:
Group TAPB-M (n=25)
Size
50
Primary endpoint
postoperative pain score by Visual analogue score at 48 hrs.
48 hours
Eligibility criteria
Inclusion Criteria: * ASA physical status I-II. * Age 20-45 years. * Undergoing lower abdominal hysterectomies. Exclusion Criteria: * Patient refusal * Patients with coagulopathy. * Hypertensive patients. * Diabetic patients. * Morbid obesity * Allergy to the used drugs
Protocol
{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'Patients will be divided in to two groups; TAPB with dexamethasone as an adjuvant to local anesthetic Gr A(n=25) and TAPB with methyl prednisolone as an adjuvant to local anesthetic Gr B(n=25).', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE', 'maskingDescription': 'The patient and assessing study outcomes will be blinded to the study group allocation.', 'whoMasked': ['PARTICIPANT', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 50, 'type': 'ACTUAL'}}
Updated at
2024-04-23

1 organization

2 products

4 indications

Indication
ultrasonography
Indication
Pain
Indication
Acute