Clinical trial

Desflurane Versus Isoflurane for Speeding Postanesthetic Recovery and Hospital Discharge: a Cluster Randomized Crossover Trial

Name

23-1049

Description

The investigators thus propose a comparative effectiveness quality improvement project to evaluate the feasibility of switching from near-exclusive use of isoflurane in adult general surgical patients to Desflurane.

Trial arms

Trial start

2024-07-01

Estimated PCD

2025-03-01

Trial end

2025-12-01

Status

Not yet recruiting

Treatment

Desflurane

General anesthesia with desflurlane

Arms:

Desflurane

Isoflurane

General anesthesia with isoflurane

Arms:

Isoflurane

Size

2619

Primary endpoint

Duration of post-anesthesia care unit recovery

1 hour

Eligibility criteria

Inclusion Criteria: * Adults having general anesthesia in the G operating room suite at the Cleveland Clinic Main Campus. Exclusion Criteria: * Operations lasting \<1.5 hours.

Protocol

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'CROSSOVER', 'interventionModelDescription': 'Randomized cluster cross-over trial', 'primaryPurpose': 'OTHER', 'maskingInfo': {'masking': 'SINGLE', 'maskingDescription': 'Patients will not be told which type of volatile anesthetic they received.', 'whoMasked': ['PARTICIPANT']}}, 'enrollmentInfo': {'count': 2619, 'type': 'ESTIMATED'}}

Updated at

2024-05-14

1 organization

2 products

1 indication

Organization

Product

Indication

Product