Clinical trial

Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia a Placebo Controlled Clinical Trial

Name

idiopathic infertility

Description

Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia

Trial arms

Trial start

2023-06-15

Estimated PCD

2024-06-01

Trial end

2024-07-01

Status

Recruiting

Phase

Early phase I

Treatment

co enzyme Q10 , L- Carnitine

Patient fulfilling inclusion criteria after obtaining consent will be randomized into four equal groups randomization will be computer based

Arms:

Group 1, Group 2, Group 3, Group 4

Size

120

Primary endpoint

Changes in Semen analysis parameters compared to baseline

6 months

Eligibility criteria

Inclusion Criteria: * of in¬fertility of 1 year or more without the use of contraception Exclusion Criteria: * o Active genital infections. * Patients with ejaculatory dysfunction * Azoospermia

Protocol

{'studyType': 'INTERVENTIONAL', 'phases': ['EARLY_PHASE1'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'CROSSOVER', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'NONE'}}, 'enrollmentInfo': {'count': 120, 'type': 'ESTIMATED'}}

Updated at

2024-04-02

1 organization

1 product

2 indications

Organization

Ain Shams University

Product

Coenzyme Q10

Indication

Infertility Unexplained

Indication

Oligospermia