Clinical trial

Dietary and Non-dietary Components of Vitamin K Metabolism

Name

R01DK069341

Description

The purpose of this study is to learn how the body responds to different amounts of vitamin K in the diet in order to understand the roles that vitamin K may have in the body. We also need to determine if older adults need more or less vitamin K in their diet compared to younger adults in order to maintain normal body stores of vitamin K.

Trial arms

Trial start

2006-05-01

Estimated PCD

2009-07-01

Trial end

2009-07-01

Status

Completed

Treatment

Vitamin K

phylloquinone (vitamin K1) 500 mcg daily in third month

Arms:

Diet Intervention

Other names:

phylloquinone

Size

Primary endpoint

Plasma Phylloquinone

2 months

Eligibility criteria

Inclusion Criteria: - Exclusion Criteria: * kidney, GI, or liver disease requiring treatment * prescribed osteoporosis medications in the previous 3 months * use of acid reducers more than twice per week * blood clotting disorder and/or abnormal clotting time * warfarin or anticoagulant use in the previous 12 months * diabetes * smoking * hormone therapy in the previous 3 months * oral contraceptive use in the previous 3 months; pregnancy * strict vegetarian diet

Protocol

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'NA', 'interventionModel': 'SINGLE_GROUP', 'primaryPurpose': 'BASIC_SCIENCE', 'maskingInfo': {'masking': 'NONE'}}, 'enrollmentInfo': {'count': 59, 'type': 'ACTUAL'}}

Updated at

2023-11-29

1 organization

1 product

2 indications

Organization

Product

Indication

Indication