Clinical trial

Comparison Between Effect of Addition of Dexamethasone and Dexmedetomidine in Combination With Bupivacaine for Pain Relief After Shoulder Arthroscopic Surgeries

Name
Assiut anesthesia g35
Description
There is a high incidence reaching up to 45%; of severe intraoperative and postoperative pain associated with arthroscopic shoulder surgery, which is often significant enough to interfere with initial recovery and rehabilitation.Various peripheral nerve blocks have been used to reduce intraoperative anesthetic requirements to improve rapid recovery and reduce postoperative pain.
Trial arms
Trial start
2023-08-01
Estimated PCD
2024-06-01
Trial end
2024-08-01
Status
Recruiting
Phase
Early phase I
Treatment
Dexmedetomidine
Dexmedetomidine will be given with bupivaciane for postoperative pain control
Arms:
dexamethasone group, dexmedetomidine group
Size
100
Primary endpoint
numerical rating pain scale
24 hours
Eligibility criteria
Inclusion Criteria: * Patients undergoing elective shoulder arthroscopy under general anesthesia Exclusion Criteria: * Contraindications to regional block (coagulopathy, infection at the needle insertion site, or diaphragmatic paralysis). * Altered conscious level. * Pregnancy. .Body mass index (BMI \> 35). * Patients who have difficulty understanding the study protocol * Patients who have any known contraindication to study medications * Patient refusal.
Protocol
{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE2', 'PHASE3'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'TRIPLE', 'whoMasked': ['PARTICIPANT', 'CARE_PROVIDER', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 100, 'type': 'ESTIMATED'}}
Updated at
2024-05-14

1 organization

1 product

1 indication

Indication
Pain Management