Traditional Chinese Herbal Medicine Buyang Huanwu Decoction on Visual Acuity and Visual Field in Patients With Normal Tension Glaucoma：a Double-blind, Randomized Controlled Trial

CMUH112-REC3-126

The goal of this clinical trial is to test Buyang Huanwu Decoction in normal intra-ocular pressure glaucoma. The main question to answer is: the effect of Buyang Huanwu Decoction and its safety in patients with normal intra-ocular pressure glaucoma. Participants will take 3 grams of Buyang Huanwu Decoction or placebo for 12 weeks. Researchers will compare treatment group and placebo group to see if the visual acuity, visual field would be improved.

2023-10-01

2024-10-31

2024-12-31

Not yet recruiting

60

Inclusion Criteria: * Diagnosis of normal tension glaucoma for at least 3 months. * Using less than 1 medicine for glaucoma. * Without any eye disease other than normal tension glaucoma. * Writing the Informed Consent Form by themselves. Exclusion Criteria: * With other chronic diseases, such as diabetes, hypertension, cancer. * With polypharmacy. * Had glaucoma surgery or myopia laser surgery before the study. * With mental disease and could not finish the study. * Allergic to Buyang Huanwu Decoction. * Pregnancy or lactation.

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'QUADRUPLE', 'whoMasked': ['PARTICIPANT', 'CARE_PROVIDER', 'INVESTIGATOR', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 60, 'type': 'ESTIMATED'}}

2023-09-28