Clinical trial

The Effect of Low Dose Ketamine on Narcotic Consumption in Patients Undergoing Laparoscopic Cholecystectomy

Name

2387-Ane-ERC-12

Description

This double-blinded randomized control trial aims to analyze the effect of low dose Ketamine on narcotic consumption, in patients undergoing Laparoscopic cholecystectomy.

Trial arms

Trial start

2013-01-17

Estimated PCD

2013-11-30

Trial end

2013-11-30

Status

Completed

Treatment

Ketamine Hydrochloride

Ketamine was given prior to wound closure.

Arms:

Ketamine group (Group K), Saline group (Group S)

Other names:

ketasol

Size

Primary endpoint

pain score using Visual Analogue scale, ranging from 0 (minimum) and 10 (maximum), 3 and below showing no pain and scores above 3 showing moderate to severe pain.

Baseline on arrival in the post anaesthesia care unit and then every fifteen minutes unto one hour

Eligibility criteria

Inclusion Criteria: * all ASA 1 and 2 patients undergoing Laparoscopic Cholecystectomy electively. Exclusion Criteria: * Hepatic and renal disease and ASA 3 and 4 patients.

Protocol

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'Randomized control trial', 'primaryPurpose': 'PREVENTION', 'maskingInfo': {'masking': 'QUADRUPLE', 'maskingDescription': 'Double blinded', 'whoMasked': ['PARTICIPANT', 'CARE_PROVIDER', 'INVESTIGATOR', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 86, 'type': 'ACTUAL'}}

Updated at

2023-07-11

1 organization

1 drug

1 indication

Organization

Aga Khan University

Drug

Ketamine

Indication

cholecystolithiasis