Glucocorticoids Associated With Antihistamines Versus Antihistamines Randomized Double Blinded for the Management of Acute Urticaria in Emergency

11 221 02

Acute urticaria is common and affected 12% of population. 400 patients come in department emergency of Toulouse each year and there aren't many studies in literature which evaluate the glucocorticoids treatment. The standard treatment of urticaria is antihistamines H1, but glucocorticoids treatment administered orally for short course would permit to increase quickly acute urticaria uncomplicated. Clinical trial, prospective randomized double blinded of adults with acute urticaria less 24 hours duration and no take treatment urticaria before.

2012-02-01

2014-02-01

2014-02-01

Completed

Early phase I

100

Inclusion Criteria: * adults * urticaria rash no more 24 h duration and no take treatment for urticaria Exclusion Criteria: * patients were presented severe anaphylaxis or taken antihistamines or glucocorticoids within 5 days of arrival at ED, * severe infection * pregnancy * patients BPCO * diabetics * allergy corticosteroids * refusal to comply * participate an other study

{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE2', 'PHASE3'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'INVESTIGATOR']}}, 'enrollmentInfo': {'count': 100, 'type': 'ACTUAL'}}

2023-05-23