Clinical trial

Adjunctive Dexmedetomidine Infusion in Non-intubated Video-assisted Thoracoscopic Surgery

Name

B202305049_V2

Description

This prospective study aims to evaluate the effectiveness of intraoperative DEX for postoperative analgesia and recovery after non-intubated VATS. In addition, the investigators observe the impact of DEX on anesthetic requirements, hemodynamic parameters, and adverse events during non-intubated VATS.

Trial arms

Trial start

2023-05-01

Estimated PCD

2025-04-01

Trial end

2025-04-01

Status

Not yet recruiting

Phase

Early phase I

Treatment

Dexmedetomidine infusion

Intraoperative dexmedetomidine infusion

Arms:

Group Dexmedetomidine, Group Saline

Size

144

Primary endpoint

Cough

Intraoperative period

Eligibility criteria

Inclusion Criteria: * American Society of Anesthesiologists (ASA) score of I-III patients receiving video-assisted thoracoscopic surgery Exclusion Criteria: * Age \< 18 or \> 80 years * ASA classifications \> III * Pregnancy * Known allergies to any drugs used in the study * Emergency surgery * Patient refusal * Chronic pain history

Protocol

{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE4'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'TRIPLE', 'whoMasked': ['PARTICIPANT', 'CARE_PROVIDER', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 144, 'type': 'ESTIMATED'}}

Updated at

2023-05-18

1 organization

1 product

3 indications

Organization

Tri-Service General Hospital

Product

Indication

Indication

Indication