Clinical trial

Comparison of the Effects of Ultrasound-Guided Combined Serratus Anterior Plane Block and Thoracic Paravertebral Block on Postoperative Acute Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery

Name
E.Kurul-E1-22-2372
Description
Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS. Analgesic methods such as thoracic paravertebral block (TPVB), intercostal block, serratus anterior plane block (SAPB), and erector spinae plane block (ESPB) are widely used for VATS. Among these methods, ultrasound (US) guided TPVB is the most preferred method. In recent years, the frequency of application of plane blocks as a component of multimodal analgesia has been increased. ESPB and SAPB are some of them. There are two techniques for SAPB application. In Deep SAPB (DSAPB) application, a local anesthetic agent is given under the serratus anterior muscle. In the Superficial SAPB (SSAPB) application, the local anesthetic agent is given above the serratus anterior muscle. Since it is done by entering from the same point in two applications, it is possible to perform these two applications at the same time with a single needle entry. The mechanisms of regional analgesia techniques used after thoracic surgery operations are also different from each other. Therefore, it may be possible to obtain a more effective analgesic effect in patients by combining the mechanism of action of DSAPB and SSAPB, as in the multimodal analgesia method. This study seeks to evaluate the effect of TPVB and combined SAPB (CSAPB) after VATS.
Trial arms
Trial start
2022-02-15
Estimated PCD
2023-05-01
Trial end
2023-05-16
Status
Completed
Treatment
Combined Serratus Anterior Plane Block
Combined deep and superficial serratus anterior plane block will be applied to the patients under real-time ultrasound guidance.
Arms:
Combined Serratus Anterior Plane Block
Other names:
Drug
Thoracic Paravertebral Block
Thoracic paravertebral block will be applied to the patients under real-time ultrasound guidance.
Arms:
Thoracic Paravertebral Block
Other names:
Drug
Size
60
Primary endpoint
Pain Scores
48 hours after surgery
Eligibility criteria
Inclusion Criteria: * 18 to 65 years old * ASA physical status I-II-III * BMI 18 to 30 kg/m2 * Elective video-assisted thoracoscopic surgery Exclusion Criteria: * Patient refusing the procedure * Emergency surgery * Chronic opioid or analgesic use
Protocol
{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 60, 'type': 'ACTUAL'}}
Updated at
2023-05-17

1 organization

1 product

7 indications

Indication
Pain
Indication
Postoperative
Indication
Video-Assisted