Clinical trial
The Effect of Allograft, Toothgraft, Alloplast on Alveolar Ridge Preservation
Name
FDASU-RecIR092210
Description
The primary objective of this study was to compare the efficacy of using allograft, autogenous tooth graft, and beta-tricalcium phosphate for alveolar ridge preservation (ARP) by examining the alveolar ridge height and width at baseline and 3 months after the ARP both clinically and radiographically. The secondary objective was to evaluate the quality of the newly formed bone using histomorphometric analysis.
Trial arms
Trial start
2017-06-20
Estimated PCD
2018-09-23
Trial end
2019-01-20
Status
Completed
Phase
Early phase I
Treatment
Toothgraft
Particulate dentin
Arms:
Alveolar ridge preservationwith tooth graft
Allograft
Mineralized corticocancellous allograft
Arms:
Alveolar ridge preservation with allograft
Other names:
Mineralized corticocancellous allograft
Alloplast
Beta tri-calcuim phosphate
Arms:
Alveolar ridge preservation with alloplast
Other names:
Beta tri-calcuim phosphate
Size
30
Primary endpoint
Clinical assessment
3 months
Clinical assessment
3 months
Eligibility criteria
Inclusion Criteria:
1. seeking implant-based restorations after tooth extraction.
2. exhibited no evidence of any significant medical history, measured using Burket's Oral medicine health history questionnaire.
3. exhibited Type I and II sockets
Exclusion Criteria:
1. nonsmokers.
2. Pregnant and breast-feeding females
3. patients with known contraindications to dental implant surgery (e.g., increased bleeding tendency, history of treatments such as radiotherapy,
Protocol
{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE3'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'TRIPLE', 'whoMasked': ['PARTICIPANT', 'INVESTIGATOR', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 30, 'type': 'ACTUAL'}}
Updated at
2023-04-19
1 organization
3 products
1 indication
Organization
Ain Shams UniversityProduct
ToothgraftIndication
Ridge EnlargementProduct
AllograftProduct
Alloplast