Clinical trial

Effects of Mulligan Technique With or Without Diclofenac Phonophoresis on Pain, Range of Motion and Functional Disability of Knee Joint in Patients With Patellofemoral Pain Syndrome

Name

REC-UOL-546-10-2023

Description

The patellofemoral pain syndrome (PFPS) is a common cause for "anterior knee pain" and mainly affects young women. the effectiveness of Mulligan technique with or without diclofenac phonophoresis on pain, range of motion and functional disability of knee joint in patients with patellofemoral pain syndrome is known little. This study, ethically approved, focused on patients with anterior knee pain referred to the Physical Therapy Department from Lahore General Hospital. After eligibility assessments and consent, participants were randomly assigned to Group A (Experimental) or Group B (Control). Over four weeks, three sessions per week, routine physiotherapy and specific exercises will be administered, with Group A receiving additional Phonophoresis using ultrasound and diclofenac gel. Outcome variables (Numeric Pain Rating Scale, KOOS-PF, Universal Goniometer) will be assessed by a blinded assessor at baseline and study completion.

Trial arms

Trial start

2023-10-18

Estimated PCD

2024-07-01

Trial end

2024-10-01

Status

Recruiting

Phase

Early phase I

Treatment

Group 1

The treatment included TENS therapy, hot pack application, stretching exercises, isometric strengthening, straight leg raises with traction, and tibial gliding techniques. Participants in Group A also received Phonophoresis as an experimental technique.

Arms:

Diclofenac Phonophoresis

Group 2

The treatment included routine physiotherapy with TENS, hot pack application, stretching exercises, isometric strengthening, straight leg raises with traction, and tibial gliding techniques.

Arms:

Mulligan Technique

Size

Primary endpoint

Numeric Pain Rating Scale

4 weeks

KOOS-PF Scale

4 weeks

Universal Goniometer

4 weeks

Eligibility criteria

Inclusion Criteria: * • Patients of age range 20-45 years and both genders (Rehman, 2021 #171) * Unilateral anterior knee pain persisting for over two months, referred by orthopedic (Rehman, 2021 #171) * Pain scoring rate on numeric pain rating scale (NPRS) \>3 during at least two activities (Rehman, 2021 #171) * Patients with positive Clarke's test/ Patellar grind test (Rehman, 2021 #171) * Pain while going up and down stairs, when sitting with knees flexed and with squatting, kneeling or returning from squat. (Powers, 2017 #172) Exclusion Criteria: * • Patients with other knee pathologies; meniscus tears, bursitis, patellar tendon injury, ligamentous injury * Degenerative joint disorders; knee osteoarthritis, rheumatoid arthritis etc. * Patellofemoral dislocation and / or frequent subluxation. * Patients having undergone lower extremity surgery * Those taking any pain medications

Protocol

{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE1', 'PHASE2'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 68, 'type': 'ESTIMATED'}}

Updated at

2024-06-03

1 organization

2 products

1 indication

Organization

University of Lahore

Product

Group 1

Indication

Patellofemoral Pain Syndrome

Product

Group 2