Pharmacokinetic Characterization of the Hemophilia A Population in Spain Using an Online Medical Application Based on a Published Population Model and a Bayesian Algorithm

PK HemoA-SP

The purpose of this study is to describe the pharmacokinetic profile of patients with hemophilia A in prophylaxis in Spain using myPKFit®

2016-11-11

2022-12-22

2022-12-22

Completed

50

Inclusion Criteria: * Male patients. * Age between 1 and 65 years old. * Patients diagnosed with Hemophilia A who are on prophylactic treatment with Advate® or Adynovi® or adjusted with myPKFIT. * Patients older than 18 who have signed the informed consent form. * In the case of mature minors, in addition to the consent signed by the legal guardian, an assent of the minor must be obtain. * In the case of patients legally incapable for giving their consent, their primary caregiver will consent as the patient's legal guardian. Exclusion Criteria: * Withdrawal of informed consent. * Patients with any medical or psychological condition that according to the researcher's criteria prevents them from following the usual clinical practice procedures. * Patients with concomitant diagnosis of other haemostasis disorders. * Patients being treated for induction of immunologic tolerance at the time of inclusion.

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2023-06-08