Clinical trial

Evaluation of the Efficacy of a Hyaluronic Acid Gel in Relieving Post-Implantation Pain: A Split-Mouth Randomized Controlled Trial

Name

UDDS-OralMed-01-2023

Description

Few previous studies have employed HA in the implant socket; instead, the majority have applied it topically to the area around dental implants after they have been placed. The application was done after suturing in these investigations. Therefore, the goal of the current study was to inject HA into the implant socket and onto the alveolar bone prior to implant insertion and suturing in order to preserve the HA for an extended period of time. This study aims to use a visual analog scale (VAS) on the first, third, and tenth days following the surgical intervention to assess the efficacy of employing HA in dental implants in terms of pain reduction that may accompany dental implant surgery.

Trial arms

Trial start

2021-02-15

Estimated PCD

2022-03-15

Trial end

2022-05-15

Status

Completed

Treatment

Hyaluronic Acid

This material will be injected into the prepared impact socket prior to inserting the implant. This injection will be done inside the socket as well as on the periphery of the socket.

Arms:

Hyaluronic acid injection

Size

Primary endpoint

Change in the Perception of pain

First assessment: at 24 hours following the surgical procedure. Second assessment: at 72 hours following the surgical intervention. Third assessment will be made on the tenth day following the surgical intervention

Eligibility criteria

Inclusion Criteria: * bilateral tooth loss with a sufficient amount of bone volume * no general problems * good oral health * age between 20 and 60 years Exclusion Criteria: * the use of immunosuppressive drugs and corticosteroids for long periods * the existence of serious systemic disorders * contraindications for local anesthesia or oral surgery * pregnant women and nursing mothers * patients receiving chemotherapy or radiation * alcoholics and heavy smokers.

Protocol

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'Split mouth design', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 11, 'type': 'ACTUAL'}}

Updated at

2023-04-07

1 organization

1 product

1 indication

Organization

Damascus University

Product

Hyaluronic Acid

Indication

Implant Complication