Clinical trial
Study of Immunity Dysfunction Induced by Extracorporeal Assistance (ECMO / ECLS)
Name
35RC16_3037_IMPECstudy
Description
Study of immunosuppression biomarkers in patients with ARDS or cardiogenic shock with ECMO / ECLS, compared to patients with ARDS or cardiogenic shock without ECMO / ECLS
Trial arms
Trial start
2017-01-01
Estimated PCD
2019-01-31
Trial end
2019-01-31
Status
Completed
Treatment
Blood test
Arms:
ECMO / ECLS, No ECMO / ECLS
Size
18
Primary endpoint
Prevalence of immunosuppression in patients with ARDS or cardiogenic shock under ECMO / ECLS hospitalized in intensive care unit
Hour 24
Eligibility criteria
Inclusion Criteria:
* Patient older than 18 years old
* Patient hospitalized in an intensive care unit
* Patient whose initial ARDS or Cardiogenic shock began less than 5 days before admission
* Patients hospitalized for ARDS or Cardiogenic shock with ECMO / ECLS or - Patients hospitalized for ARDS or Cardiogenic shock without ECMO / ECLS
Exclusion Criteria:
* Opposition of patient, relative or legal representative for participation in the study
* Pregnant woman
* Pre-immunodepression
* Implementation of immunosuppressive therapy such as chemotherapy, cyclophosphamide, high-dose corticosteroids (\> 0.5mg / kg / day).
Protocol
{'studyType': 'OBSERVATIONAL', 'patientRegistry': False, 'designInfo': {'observationalModel': 'COHORT', 'timePerspective': 'PROSPECTIVE'}, 'bioSpec': {'retention': 'SAMPLES_WITHOUT_DNA', 'description': 'plasma'}, 'enrollmentInfo': {'count': 18, 'type': 'ACTUAL'}}
Updated at
2023-04-12
1 organization
1 product
2 indications
Organization
Rennes University HospitalProduct
Blood testIndication
Acute Respiratory Distress SyndromeIndication
Cardiogenic Shock