Multimodal Periarticular Analgesic Injection With and Without Surgeon-Administered Adductor Canal Block During Total Knee Arthroplasty: A Randomized Controlled Trial

9172

The investigators aim to investigate whether the addition of a surgeon-administered adductor canal blockade to a multimodal periarticular injection cocktail provides additional pain relief for patients undergoing total knee arthroplasty. This study will help identify the effectiveness of surgeon-administered adductor canal blockade in perioperative pain control for patients undergoing total knee arthroplasty

2020-10-09

2024-12-01

2025-07-01

Early phase I

130

Inclusion Criteria: 1. Patients age 30-85undergoing first-time primary unilateral total knee arthroplasty for osteoarthritis and remaining hospitalized for at least one night Exclusion Criteria: 1. Patients undergoing revision total knee arthroplasty 2. Patients undergoing bilateral total knee arthroplasty 3. Workers compensation patients 4. Patients undergoing total knee arthroplasty for post-traumatic arthritis 5. Patients with inflammatory arthritis 6. Patients with any previous surgery on the operative knee which involved an arthrotomy 7. Patients taking opioids prior to total knee arthroplasty 8. Patients with a known history of drug or alcohol abuse 9. Patients undergoing total knee arthroplasty at an ambulatory surgery center, or being discharged home from the hospital on the same day as their procedure (planned) 10. Patients who have had a total knee arthroplasty performed on the contralateral knee

{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE2', 'PHASE3'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE', 'maskingDescription': 'Both the investigator and participant will be blinded to the injection administered perioperatively', 'whoMasked': ['PARTICIPANT', 'INVESTIGATOR']}}, 'enrollmentInfo': {'count': 130, 'type': 'ESTIMATED'}}

2024-04-02