Efficacy of Piroxicam as a Perioperative Analgesic for Patients Undergoing Fixation of Maxillofacial Fractures

FMASU R 54/ 2018

At Eldemerdash Hospital at Ain Shams University in Egypt, 72 adult patients (16 to 25 years old) who had mandibular or maxillary fractures were treated with open reduction and internal stabilization. Patients were divided into two categories. (31 patients each) Using randomly generated data from computer, the piroxicam group received 0.4 mg/kg of intramuscular piroxicam, while the general anesthesia group (GA group) did not receive piroxicam. The overall amount of rescue analgesic dosage and postoperative complications like nausea and vomiting were therefore included in the outcomes measurement.

2019-08-16

2022-04-30

2022-12-31

Completed

Early phase I

72

Inclusion Criteria: * patients aged from 16-25 years old * ASAI II * scheduled for open reduction and internal fixation of mandibular or maxillary fractures Exclusion Criteria: * a history of convulsion, * gastrodudenal ulcer * hematological disorders * patient suffering from hepatic or renal dysfunction * concomitant use of anticoagulants * refusal of the patients to participate * patients younger than 12 years

{'studyType': 'INTERVENTIONAL', 'phases': ['EARLY_PHASE1'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 72, 'type': 'ACTUAL'}}

2023-03-21