Comparison of A-PRF vs Bone Wax in Hemostasis, Pain Relief and Healing Following Exodontia: A Single-blind Randomised Control Trial

F.2-81/2022-GENL/338/JPMC

The goal of this clinical trial is to compare the pain relief and healing effect of A-PRF and Bone-wax in patients having mandibular tooth-extractions. The main question\[s\] it aims to answer are: In the perspective of improvement in pain and healing; * Does A-PRF performs better than control group? * Does Bone-wax performs better than control group? * Healing index and Pain scale score Comparison of A-PRF and Bone-wax; if one is better than the other? Participants will be asked to give resoponse to a post-operative symptom severiety (PoSSe) scale. An investigator will score the patient's extraction for hemostasis and on healing index \[describe the main tasks participants will be asked to do, treatments they'll be given and use bullets if it is more than 2 items\]. If there is a comparison group: Researchers will compare \[insert groups\] to see if \[insert effects\].

2023-01-01

2023-06-30

2023-09-30

Recruiting

129

Inclusion Criteria: * All patients who need extraction of mandibular posterior teeth * Overall, systemically healthy individuals (Established based on history, i.e., patients who do not take medicine for any systemic condition). * INR within normal range. Exclusion Criteria: * Patients with a diagnosed systemic condition. * Patients who are immunocompromised. * Patients who are unwilling to participate or withdraw from the study. * Patients who fail to report on the seventh and twenty-first post-extraction day. * Patients with physical or mental impairments who need assistance in taking their medications.

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['PARTICIPANT']}}, 'enrollmentInfo': {'count': 129, 'type': 'ESTIMATED'}}

2023-02-27