Clinical trial

Effects of Antimicrobial Photodynamic Therapy Associated to Biomaterials on Regeneration of Class II Furcation Lesions

Name

BauruSchoolDentistryfurcation

Description

The aim of this study is to evaluate the additional effect of antimicrobial photodynamic therapy regeneration treatment of mandibular furcation lesions when associated to bovine bone and porcine collagen membrane.

Trial arms

Trial start

2017-04-02

Estimated PCD

2018-12-22

Trial end

2018-12-22

Status

Completed

Treatment

Scaling and root planing

Furcation treatment by scaling and root planing

Arms:

Antimicrobial Photodynamic Therapy, Control

Toluidine Blue O

Antimicrobial photodynamic therapy with toluidine blue O (10mg/ml) and red laser.

Arms:

Antimicrobial Photodynamic Therapy

Other names:

Antimicrobial photodynamic therapy

Size

Primary endpoint

Horizontal probing depth

one year

Tomographic Bone filling

One year

Eligibility criteria

Inclusion Criteria: * Clinical diagnosis of class II furcation lesion in mandibular 1st and 2nd molars * Mandibular 1st and 2nd molars without caries, erosion or abrasion Exclusion Criteria: * Smoking habit * Pregnancy * Use of antibiotics in the last six months * Periodontal treatment in the last six months * Endodontic lesion * Systemic diseases that impair wound healing

Protocol

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'Split-mouth design. One side of mouth is test and the other is control side.', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 25, 'type': 'ACTUAL'}}

Updated at

2023-02-27

1 organization

1 product

4 indications

Organization

University of Sao Paulo

Product

Indication

Indication

Indication

Indication

Periodontal Bone Loss