The Effect of Dionegest Use on the Frequency of Fibromyalgia in Endometriosis: A Cross-sectional Observational Study.

GaziosmanpaşaTREHh

Endometriosis usually occurs during the reproductive period of women and poses a significant burden on quality of life and social costs. The estimated prevalence in premenopausal women is 10% in clinical studies and the frequency rises to 50% in symptomatic patients with pelvic pain and infertility. Observational studies in Europe estimated the prevalence to be 8-15 per 1000 people. Fibromyalgia is a common musculoskeletal chronic painful condition that may be accompanied by cognitive impairment, somatic symptoms, fatigue, and psychiatric symptoms. The population frequency is given as 20-80 per 1000 people. Fibromyalgia is most often diagnosed in women aged 20-55 years; prevalence increases with age and is associated with a higher prevalence of comorbidities, including endocrine and genitourinary disorders. Co-existance of endometriosis and fibromyalgia is a special entity that has not been enlightened in detal yet.

2021-06-30

2022-03-15

2022-04-30

Completed

61

Inclusion Criteria: * 18 - 40 years old * Nulliparity * Women diagnosed with endometrioma (unilateral, ≤ 4cm) by physical examination and vaginal/transabdominal ultrasonography Exclusion Criteria: * Pelvic mass that cannot be differentially diagnosed by physical examination and imaging techniques * Endometrioma cases with surgical treatment indication * Any concurrent major psychiatric disorder * Any medical condition that may interfere with sensory perception (diabetes, neurological disorder, etc.) * Presence of any other concomitant painful condition other than fibromyalgia and endometriosis * Currently using any hormonal therapy * History and/or presence of malignancy * Pregnancy * Menopause or premature ovarian failure

{'studyType': 'OBSERVATIONAL', 'patientRegistry': False, 'designInfo': {'observationalModel': 'CASE_ONLY', 'timePerspective': 'PROSPECTIVE'}, 'enrollmentInfo': {'count': 61, 'type': 'ACTUAL'}}

2023-02-23