Clinical trial
Microneedling With Topical Glycolic Acid 35% Versus Microneedling With Topical Insulin in the Treatment of Atrophic Post-acne Scars
Name
atrophic post-acne scars
Description
To examine the anti-scarring effect of topical glycolic acid 35% combined with microneedling against that of topical insulin combined with microneedling for post acne scars
Trial arms
Trial start
2023-02-22
Estimated PCD
2023-09-01
Trial end
2023-12-01
Status
Not yet recruiting
Treatment
microneedling with topical glycolic acid 35%.
15 patients will be subjected to microneedling with topical glycolic acid 35%. Selected patients will receive one session of microneedling combined with a topical agent, with two weeks interval till complete clearance or up to 6 sessions.
Arms:
Glycolic acid 35% group
microneedling with topical human insulin solution.
15 patients will be subjected to microneedling with topical human insulin solution. Selected patients will receive one session of microneedling combined with a topical agent, with two weeks interval till complete clearance or up to 6 sessions.
Arms:
topical insulin group
Size
30
Primary endpoint
Goodman and Baron's acne scar grading system
through study completion, an average of 1 year
Quartile grading system
through study completion, an average of 1 year
5 point scale for evaluating patient's satisfaction
through study completion, an average of 1 year
Pain assessment
through study completion, an average of 1 year
Eligibility criteria
Inclusion Criteria:
* All types of facial atrophic acne scars
* Patients aged \>18 years
* Both sexes
Exclusion Criteria:
* Pregnancy and lactation
* Active acne or any active facial lesion
* History of keloid scar
* History of systemic diseases as DM or hypotension
* Bleeding and coagulation disorders
* Infection and immunosuppression
Protocol
{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['PARTICIPANT']}}, 'enrollmentInfo': {'count': 30, 'type': 'ESTIMATED'}}
Updated at
2023-02-21
1 organization
2 products
1 indication
Organization
Zagazig University