Clinical trial

Dental Care and Initiation of Anti-osteoporotic Therapy

Name
22Rhumato04
Description
The initiation of bisphosphonate therapy for osteoporosis requires an assessment of the oral status to prevent the risk of osteonecrosis of the jaw. This recommendation is sometimes a hindrance to the initiation of treatment or may be responsible for a delay in treatment or even the failure to initiate treatment. However, in the case of a severe osteoporotic fracture (femoral or humeral neck fracture, vertebral fracture or pelvic fracture), treatment must be rapid because of the major risk of refracture in the short term (multiplied by 5 in the 2 years following the fracture). In the rheumatology department of the Nice University Hospital, the investigator team take care of patients with osteoporotic fractures either directly in hospital or referred by the orthopedics department as part of a care program. For these patients, the team perform an etiological assessment, bone densitometry and evaluation of the oral status with dental panoramic and tele-expertise to determine if there is an indication to perform surgical care before starting the treatment. Therefore, the investigator aimed to describe the number of patients requiring dental surgery befor the initiation of bisphosphonate or denosumab treatment before to introduce treatment for osteoporosis
Trial arms
Trial start
2019-01-03
Estimated PCD
2022-01-04
Trial end
2022-01-04
Status
Completed
Treatment
biphosphonates
Initiation of bisphosphonate therapy
Arms:
Treatment initiation
Dental care
Surgical dental care
Arms:
Surgical dental care
Size
338
Primary endpoint
Number of patients requiring surgical dental care
15 months
Eligibility criteria
Inclusion Criteria: * osteoporotic fracture requiring treatment with bisphosphonate or denosumab Exclusion Criteria: * osteoporotic fracture requiring teriparatide treatment
Protocol
{'studyType': 'OBSERVATIONAL', 'patientRegistry': False, 'designInfo': {'observationalModel': 'OTHER', 'timePerspective': 'RETROSPECTIVE'}, 'enrollmentInfo': {'count': 338, 'type': 'ACTUAL'}}
Updated at
2023-02-09

1 organization

1 product

2 indications

Indication
Oral Health
Indication
Osteoporosis