Histological and Radiographic Evaluation of the Effects of Direct Pulp Capping Agent on Human Pulp Tissue

2264

This in- vivo study was conducted to evaluate the response of human pulp tissue following direct pulp capping using four different pulp capping agents in premolars scheduled for extraction in patients undergoing orthodontic treatment.

2024-04-01

2024-06-01

2024-07-01

Recruiting

Early phase I

40

INCLUSION CRITERIA: * CARIES-free, undamaged mature maxillary and mandibular premolars that were planned for extraction for orthodontic reasons. * Teeth that show no reaction to percussion. * Teeth with no previous restorations. * Teeth that show vitality, when checked with an electric pulp tester. * Teeth that show no signs of caries or periapical pathology when examined * radiographically. * Fully erupted teeth, that allowed proper application of rubber dam. EXCLUSION CRITERIA: * caries are present * Teeth with signs and symptoms of irreversible pulpitis, such as nighttime severe pain * or spontaneous pain. * Teeth that show sensitivity to hot and/or cold. * Radiographic examination reveals any signs of caries, periapical pathology, * internal/external root resorption, furcal radiolucency/ inter-radicular bone destruction * and/or calcifications in the pulp chamber or canals. * Medically compromised patient. * Pregnant patient.

{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE4'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['PARTICIPANT']}}, 'enrollmentInfo': {'count': 40, 'type': 'ESTIMATED'}}

2024-05-30