Clinical trial

Comparison of Pericapsular Nerve Group Block With Lateral Femoral Cutaneous Nerve Block and Quadratus Lumborum Block for Total Hip Arthroplasty

Name
2021-541
Description
Adequate pain management following total hip arthroplasty (THA) is a key component for patient satisfaction and early ambulation. However, due to the complexity of the innervation of the hip joint, the most appropriate anaesthetic and analgesic technique for THA remains unclear. A femoral nerve block is commonly performed and well established but is associated with motor weakness. Recently, the pericapsular nerve group (PENG) block has been introduced as an effective choice which targets the articular branches of the hip. The quadratus lumborum block (QLB) is a relatively new regional block that has been reported to provide effective analgesia for THA. The main objective of this study is to compare the effectiveness of the ultrasound-guided PENG block technique compared to QLB block in terms of efficacy of pain control and the safety profile after total hip arthroplasty under spinal anesthesia.
Trial arms
Trial start
2022-01-01
Estimated PCD
2023-04-10
Trial end
2023-04-21
Status
Completed
Treatment
PENG/LFCN and QL Blocks
Bupivacaine 0.25% injection
Arms:
Group PENG+LFCN Block, Group QL Block
Size
80
Primary endpoint
Pain scores
Changes from baseline opioid consumption at postoperative 0, 2, 6, 12 and 24 hours
Opioid consumption
Changes from baseline opioid consumption at postoperative 0, 2, 6, 12 and 24 hours
Eligibility criteria
Inclusion Criteria: Physical status according to American Society of Anesthesiologists (ASA ) I-III Exclusion Criteria: * Younger than 40 years old and older than 85 * Patients undergoing general anesthesia * Allergy or intolerance to one of the study medications * Infection of the skin at the site of the needle puncture, * Patients who do not accept the procedure * History of bleeding diathesis * ASA IV, * Chronic gabapentin/pregabalin,opioid use * Hepatic or renal insufficiency * Previous operation on the same hip * BMI \>40
Protocol
{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'Parallel Assignment', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE', 'maskingDescription': 'The patient, and the outcomes assessor who performs postoperative pain evaluation will not know the group.', 'whoMasked': ['PARTICIPANT', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 80, 'type': 'ACTUAL'}}
Updated at
2023-05-03

1 organization

1 product

3 indications