The Use of Selective Alpha Blockers (Silodosin) in Management of Lower Ureteral Stones Larger Than 6 mm in Diameter

No 475

This research aims to study the effectiveness of silodosin in the management of lower ureter stones larger than 6 mm in diameter in terms of affected ureter (right or left), the size of the stone, the degree of hydronephrosis, the rate of stone expulsion(day), whether the stone was completely expelled or not, and the side effects of silodosin.

2022-10-20

2023-10-20

2023-10-25

Completed

Early phase I

100

Inclusion Criteria: * Patients attending the urology Clinic with a distal unilateral ureteral stone larger than 6 mm in diameter. Exclusion Criteria: * Patients under 18 years of age * Pregnant women * Patients with whom we were unable to contact * Patients treated with silodosin for another reason * Single kidney patients * Patients with bilateral ureter stones * Patients with deteriorating kidney function * Patients with grades 3rd and 4th of hydronephrosis

{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE1', 'PHASE2'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'NONE'}}, 'enrollmentInfo': {'count': 100, 'type': 'ACTUAL'}}

2024-04-24