Evaluation of the Effects of Tranexamic Acid and Chlorhexidine Gel on Alveolar Osteitis Incidence

RTEUni

This intervention is the treatment of alveolar osteitis (alveolitis) with different effects, which occurs due to the formation of clot after extraction, which is one of the most common intervals after tooth extraction.98 healthy patients with molar and premolar teeth with indication for extraction were taken to the Recep Tayyip Erdoğan University Faculty of Dentistry, Department of Oral and Maxillofacial Diseases and Surgery clinic between May 2024 and June 2024 (age: 38 sessions: 19). -62) 113 teeth (85 molar, 28 premolar teeth) were treated with Spongostan placed in the tooth socket after extraction, spongostan with Chlorhexidine gel and spongostan with tranexamic acid, randomly distributed. After extraction, alveolitis was observed and evaluated prospectively using spongostan, chlorhexidine gel and tranexamic acid in the dental sockets. The researcher checked the participants on the 3rd and 7th days after the tooth extraction. The researcher recorded the pain and edema levels by asking the participants between 0 and 10 using the Visual Analogue Scale (VAS). The researcher filled in the forms for the presence of halitosis, trismus and exposed bone socket on the 3rd and 7th days (YES-NO). Permanent analyzes of the study were created with the SPSS package program.

2024-05-16

2024-05-26

2024-06-01

Active (not recruiting)

98

Inclusion Criteria: 1. Healthy individuals between the ages of 18-65 2. Molar and premolar teeth with extraction indication Exclusion Criteria: 1. Against drugs or substances to be used in surgery (articaine, tranexamic acid, chlorhexidine) have allergies, 2. Those who used antibiotics 30 days before the dental extraction, 3. Clinical and radiological examinations in the operation area 30 days before dental extraction and/or on the day of the procedure. Any signs of pathology and infection (such as periapical pathology, pericoronitis), 4. Those who routinely use oral antiseptics, 5. Systemic fever, absence of growth such as lymphadenopathy (LAP), 6. Women are lactating or pregnant, 7. Using oral contraceptives, 8. Procedures that were not attended to control appointments (day 3-7) were not included.

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'PREVENTION', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'INVESTIGATOR']}}, 'enrollmentInfo': {'count': 98, 'type': 'ACTUAL'}}

2024-05-30