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Clinical trial

Effect of Adding Magnesium Sulphate to Bupivacaine on the Quality of Ultrasound-guided Serratus Plane Block in Patients Undergoing a Modified Radical Mastectomy

ID
Name
SAP Block in Mastectomy
Description
To decrease post-operative pain in patients undergoing modified radical mastectomy.
Trial arms
Trial start
2017-08-15
Estimated PCD
2018-12-11
Trial end
2019-01-09
Status
Completed
Treatment
Magnesium Sulphate
adding magnesium sulphate to local anaesthetic in SAP Block
Arms:
magnesium sulphate group
Other names:
MgSO4
Normal saline
adding normal saline to local anaesthetic in SAP block
Arms:
control group
Other names:
NaCl
Size
40
Primary endpoint
The duration of analgesia measured by the time of first analgesic request
post operative 24 hours
Eligibility criteria
Inclusion Criteria: * Adult, female patients, ASA physical status I, II, and III aged older than 18 years scheduled for modified radical mastectomy surgery under general anesthesia. Exclusion Criteria: Any known allergies to the study drugs. Anatomical abnormalities or infections in the serratus region. Bleeding disorders e.g. thrombocytopenia, high INR, high PT in chronic liver or impaired kidney). Patients on chronic pain medications or regularly receiving analgesics. Pregnant or breast feeding patients. Body Mass Index (BMI) more than 35.
Protocol
{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'CARE_PROVIDER']}}, 'enrollmentInfo': {'count': 40, 'type': 'ACTUAL'}}
Updated at
2024-04-10

1 organization

1 product

1 drug

1 indication

Organization
Suez Canal University
Product
Magnesium Sulphate
Indication
Serratus Anterior Plane Block
Drug
Varlilumab