Comparison of Postoperative Analgesic Effects of Ultrasonography-Guided Paravertebral Block and Subcostal Transversus Abdominis Plane Block in Patients Undergoing Laparoscopic Nephrectomy

2022-1276671

Most of the patients undergoing laparoscopic partial/radical nephrectomy can experience moderate or severe postoperative pain, and inadequate control of this pain can cause negative consequences such as development of chronic pain, pulmonary and cardiac events, and side effects of long term opioid usage. Due to these adverse outcomes, ultrasonography-guided plane blocks can be beneficial for these patients to decrease opioid consumption. In this study, the investigators aim to compare ultrasonography-guided plane blocks: Paravertebral block and subcostal transversus abdominis plane block and traditional method: patient controlled analgesia with opioids. The investigators hypothesized that analgesic efficacy in both paravertebral and subcostal TAP blocks will have similar outcomes but better than traditional method.

2023-02-15

2023-10-01

2024-02-01

Completed

91

Inclusion Criteria: * Age of 18-75 * Patients who are ASA (American Society of Anesthesiology): I-II * Patients who will have laparoscopic partial/radical nephrectomy * Patients who volunteer to participate in the study Exclusion Criteria: * Patients with any kind of coagulopathy * Patients with severe cardiac, pulmonary, renal or liver disease * Patients who have difficulty comprehending the IV PCA device * Patients with local anesthetic allergy * Patients with chronic opioid use

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'RANDOMISED SINGLE BLINDED INTERVENTIONAL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 91, 'type': 'ACTUAL'}}

2024-03-12