The Desensitising Effect of Nanosilver Fluoride Compared to Low-Level Laser Therapy in Molar-Incisor Hypomineralisation: A Randomised Controlled Clinical Trial

0797-11/2023

The aim of the current study is to assess the desensitising effect of nanosilver fluoride on first permanent molars (FPMs) in patients with MIH in comparison to low-level laser therapy.

2024-04-01

2024-06-01

2024-07-01

Active (not recruiting)

Early phase I

120

Inclusion Criteria: * The presence of at least one hypersensitive first permanent molar in MIH patient (using the Schiff Cold Air Sensitivity Scale (SCASS)). * Completion of an informed consent to participate in the study. Exclusion Criteria: * Hypomineralised molars resulting from other medical conditions, such as enamel malformations associated with syndromes, dental fluorosis, enamel hypoplasia, amelogenesis imperfecta, and dental caries. * The presence of active tooth decay or defective restorations in the tooth under examination which can confound the aetiology of hypersensitivity with pulpitis. * The presence of pulpal symptoms. * Having undergone any professional desensitising treatment in the previous 6 months. * Having used a desensitising paste other than habitual toothpaste in the previous 3 months. * Use of anti-inflammatory drugs or analgesics at the time of recruitment. * Allergy or sensitivity to silver or any of the materials included in the study.

{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE2', 'PHASE3'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 120, 'type': 'ESTIMATED'}}

2024-06-04