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Clinical trial

Comparison of Oral Isotretinoin Versus Ancomparison of Oral Isotretinoin Versus Antibiotics on Corneal Thickness in Patients With Acne Vulgaris

ID
Name
MSRSW/Batch-Fall22/731
Description
Comparison of Oral Isotretinoin versus comparison of Oral Isotretinoin versus Antibiotics on Corneal Thickness in Patients with Acne Vulgaris
Trial arms
Trial start
2023-11-01
Estimated PCD
2024-06-01
Trial end
2024-10-30
Status
Active (not recruiting)
Treatment
Oral Isotretinoin
20 mg/kg/day that affects sebaceous glands and is used to treat severe acne Frequency: Once daily
Arms:
Oral Isotretinoin
Antibiotics
250 mg on laternate day/3 months Frequency: Once or twice daily
Arms:
Antibiotics
Size
36
Primary endpoint
Optical Coherence Tomography (OCT)
12 Months
Snellen Chart
12 months
Eligibility criteria
Inclusion Criteria: * Patients of either gender shall be enrolled for this study. * Acne vulgaris patients taking oral isotretinoin and oral antibiotics shall be included. Exclusion Criteria: * Patients with any ocular pathology shall be excluded. * Patients with any systemic pathology other than acne vulgaris shall be excluded. * Patients with history of contact lens wear, previous refractive surgery or injury shall be excluded.
Protocol
{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'HEALTH_SERVICES_RESEARCH', 'maskingInfo': {'masking': 'NONE'}}, 'enrollmentInfo': {'count': 36, 'type': 'ACTUAL'}}
Updated at
2024-07-02

1 organization

1 product

1 indication

Organization
Superior University
Product
Antibiotics
Indication
Cornea