Weight Loss and Treatment Patterns in a Real World Population of Adults Receiving Saxenda® for Weight Management in Routine Clinical Practice in Switzerland

NN8022-4823

The study is investigating weight loss and treatment patterns associated with the use of Saxenda® in adult patients. The aim of the study is to assess the weight loss associated with Saxenda® in patients with obesity or overweight. Saxenda® was prescribed to participants by study doctor independently of this study. The study will last for about 4 months, where the data will be collected from the available medical records. There will be no additional activities expected from participants in the scope of study because it is a chart-review study.

2021-12-03

2022-04-15

2022-04-15

Completed

269

Inclusion Criteria: * Signed consent (general consent for research or study-specific informed consent) obtained before any study-related activities (study-related activities are any procedure related to recording of data according to the protocol). * Male or female, aged 18 to 74 years (both inclusive) at the time of Saxenda® initiation. * Have been prescribed Saxenda® for weight management. * For the reimbursed cohort, per the Swiss reimbursement criteria: BMI greater than or equal to 35 kg/m\^2 or a BMIgreater than or equal to 28 and below 35 kg/m\^2 with additional weight related comorbidities (pre diabetes or T2D (Type 2 Diabetes Mellitus), hypertension, dyslipidaemia), prior to receiving the Saxenda® treatment. * For the non-reimbursed cohort, BMI greater than or equal to 30 kg/m\^2 or a BMI greater than or equal to 28 kg/m\^2 with additional weight related comorbidities (pre diabetes or T2D, arterial hypertension, dyslipidaemia), prior to receiving the Saxenda® treatment. * The decision to initiate treatment with commercially available Saxenda® has been made by the patient/legally acceptable representative (LAR) and the treating physician before and independently from the decision to include the patient in this study. * Baseline weight measurement within 3 months of Saxenda® initiation/prescription. * At least one weight assessment post-Saxenda® initiation/prescription. Exclusion Criteria: * Previous participation in this study. Participation is defined as having given informed consent in this study. * Treatment with any investigational drug within 30 days of Saxenda® prescription/initiation. * Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation. * Concomitant treatment of Saxenda® with other GLP 1 (Glucagon-like peptide-1) receptor agonists, or orlistat. * Concomitant treatment with sodium/glucose cotransporter-2 inhibitors (SGLT 2i), dipeptidyl peptidase-4 (DPP 4i), or insulin for the reimbursed cohort only. * Patients who have been treated with any obesity medication for last 12 weeks prior to initiation of Saxenda® treatment. * Patients who have previously been treated with a GLP 1 receptor agonist for the reimbursed cohort only. * Patients who have undergone bariatric surgery at any time before starting Saxenda® treatment. * Patients initiating Saxenda® treatment after 31 October 2020.

{'studyType': 'OBSERVATIONAL', 'patientRegistry': False, 'designInfo': {'observationalModel': 'COHORT', 'timePerspective': 'RETROSPECTIVE'}, 'enrollmentInfo': {'count': 269, 'type': 'ACTUAL'}}

2022-11-17