Pilot, Double-Blind, Placebo-Controlled, Parallel Group Study of the Safety Clinical Activity of CCX282-B in Patients With Moderate to Severe Crohn's Disease

CL003_282

The purpose of this research study is to investigate the effects of an investigational medication, called CCX282-B, on safety and on the some of the symptoms of Crohn's Disease in patients who are experiencing an active flare-up of moderate to severe Crohn's Disease.

2004-08-01

2005-12-01

Completed

Early phase I

70

Inclusion Criteria: * Diagnosis of moderate to severe Crohn's Disease in small intestine; disease must be active at the time of study entry * Use of adequate and approved methods of birth control throughout the study period * Willing and able to sign an informed consent Exclusion Criteria: * Pregnant or breastfeeding * Infection with hepatitis B, hepatitis C, or human immunodeficiency virus (HIV; the virus that causes AIDS) * Abuse of alcohol or of illegal drugs

{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE2'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE'}}, 'enrollmentInfo': {'count': 70}}

2023-08-25