Valacyclovir Monotherapy in Pain Management of Acute Apical Abscesses After Performing Emergency Chamber Opening; A Randomized Clinical Trial

2517

This study is aimed to evaluate the efficacy of valacyclovir in reducing postoperative pain following emergency chamber opening for acute apical abscess . There will be 82 participants, (41 in each group) Group A will receive Valacyclovir Group B will receive standard treatment i.e. Naproxen Sodium. Pain level will be assessed by using Numeric rating scale for 6 days

2024-03-27

2024-04-01

2024-05-01

Recruiting

Early phase I

82

Inclusion Criteria: * Patient Age ≥18 years old * Healthy patient American Society of Anesthesiologists (ASA) class l and ll. * Patients having clinical evidence of pulp necrosis and acute apical abscess with radiographic signs of periapical disease. * Main inclusion criteria is that patient should have moderate to severe pain, it can be calculated as: 1 to 3 as Mild pain. 4 to 6 as moderate pain. 7 to 10 as severe pain. Exclusion Criteria: * Patient currently on antibiotics or antivirals * Smokers * Unusual tooth anatomy or inaccurate diagnosis * Pregnant or nursing mothers * Patients allergic to valacyclovir

{'studyType': 'INTERVENTIONAL', 'phases': ['PHASE4'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'TRIPLE', 'whoMasked': ['PARTICIPANT', 'INVESTIGATOR', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 82, 'type': 'ESTIMATED'}}

2024-04-10