Therapeutic Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis and Periarticular Tissue Injury

KY20232210

To evaluate the safety and effectiveness of PRP injection therapy in the repair of osteoarthritis and periarticular soft tissue injury through a single-center, exploratory clinical study, and to provide a more reliable basis for the treatment of joint injury.

2023-09-01

2025-12-31

2025-12-31

Recruiting

300

Inclusion Criteria: * The age range of the participants was 20 to 60 years old. Through a comprehensive clinical and imaging examination, it was conclusively determined that the individuals had knee osteoarthritis or experienced injuries to the cart, and meniscus surrounding the knee joint. * The preoperative routine tests and examinations revealed no contraindications. * Revised sentence: "Informed consent of the patient Exclusion Criteria: * The platelet count or function exhibits significant abnormalities、Systemic infection transmitted through the bloodstream. * Prolonged usage of anti-inflammatory drugs and systemic corticoid administration. * In injection site or damage to the skin. * Patients with tumors or undergoing radiotherapy and chemotherapy. * Pregnant or breastfeeding women. * Individuals with mental illnesses who are unable to cooperate with follow-up procedures. * Contraindications for MRI、Patients or their families do consent to participate in the study. * Other circumstances that render participation in the study unsuitable.

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'OUTCOMES_ASSESSOR']}}, 'enrollmentInfo': {'count': 300, 'type': 'ESTIMATED'}}

2023-10-13